Mortality in Elderly Patients Taking Furosemide: Prospective Cohorts Study

Table 4

Multivariate models of mortality at 5 years.

N = 597	HR	IC 95%
Age	1.10	1.07–1.13	<0.01
Sex (men vs. women)	1.96	1.32–2.91	<0.01
Smoking (yes vs. no)	0.94	0.70–1.26	0.66
Functional capacity (Katz index)	1.14	1.02–1.26	0.02
Muscle strength	0.99	0.97–1.01	0.17
Comorbidity	1.07	0.98–1.16	0.14
Cognition Pfeiffer index	1.13	1.05–1.22	<0.01
Heart disease	0.94	0.69–1.28	0.69
Diastolic blood pressure	0.99	0.98–1.00	0.03
Pulse pressure	1.00	0.99–1.01	0.91
Furosemide (yes vs. no)	2.31	1.48–3.61	<0.01
Nitrites (yes vs. no)	0.40	0.86–2.57	0.16
Furosemide—nitrites (interaction)	0.87	0.29–2.58	0.80