Research Article
Mortality in Elderly Patients Taking Furosemide: Prospective Cohorts Study
Table 3
Relationship between drug exposure and mortality at 5 years (univariate analysis).
| | Deceased exposed | Deceased not exposed | Odds ratio | 95% CI | |
| ACE inhibitors | 56 (41%) | 170 (31%) | 1.52 | 1.02–2.26 | 0.042 | ARB | 39 (30%) | 187 (34%) | 0.87 | 0.56–1.33 | 0.533 | Beta-blockers | 22 (30%) | 204 (33%) | 0.87 | 0.50–1.48 | 0.693 | Calcium antagonists | 32 (30%) | 194 (33%) | 0.88 | 0.55–1.34 | 0.652 | Alpha-blockers | 17 (44%) | 209 (32%) | 1.62 | 0.84–3.15 | 0.199 | Nitrites | 20 (61%) | 206 (32%) | 3.33 | 1.63–7.14 | 0.001 | Diuretics | 86 (45%) | 140 (28%) | 2.04 | 1.43–2.93 | 0.001 | Torasemide | 21 (41%) | 205 (32%) | 1.47 | 0.79–2.69 | 0.216 | Spironolacton | 13 (54%) | 213 (32%) | 2.49 | 1.09–6.00 | 0.044 | Chlorthalidone | 1 (11%) | 225 (33%) | 0.25 | 0.01–1.63 | 0.283 | Hydrochlorothiazide | 18 (38%) | 208 (33%) | 1.24 | 0.65–2.31 | 0.525 | Indapamide | 4 (31%) | 222 (33%) | 0.90 | 0.26–2.89 | 1.000 | Amiloride | 6 (46%) | 220 (33%) | 1.76 | 0.58–5.79 | 0.373 | Furosemide | 38 (68%) | 188 (30%) | 4.95 | 2.77–9.09 | <0.001 |
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