C-Reactive Protein Levels in relation to Incidence of Hypertension in Chinese Adults: Longitudinal Analyses from the China Health and Nutrition Survey

Table 4

Multivariable-adjusted odds ratios of hypertension according to categories of hs-CRP in follow-up studies from 2009 to 2015 (n = 3794).

Total	0 ≤ hs-CRP < 1	1 ≤ hs-CRP < 3	3 ≤ hs-CRP < 10	p	R^2	R^2change^#
Patient/total participants	200/1135	521/2015	191/644
Crude OR (95% CI)^1	Ref	1.630 (1.359, 1.956)	1.971 (1.570, 2.476)	<0.001	0.0163	—
Adjusted OR (95% CI)^2	Ref	1.401 (1.159, 1.690)	1.572 (1.240, 1.992)	<0.001	0.0893	0.073
Adjusted OR (95% CI)^3	Ref	1.473 (1.163, 1.866)	1.571 (1.145, 2.154)	0.001	0.0727	−0.016
Adjusted OR (95% CI)^4	Ref	1.359 (1.037, 1.782)	1.621 (1.137, 2.310)	0.005	0.1422	0.069
Adjusted OR (95% CI)^5	Ref	1.279 (0.793, 1.683)	1.462 (1.018, 2.101)	0.030	0.1501	0.008

¹Model 1: original model without any adjustments; ²model 2: adjusted for place of residence, age, gender, nationality, and education; ³model 3: adjusted as for model 2 plus smoking status, alcohol consumption, sleep duration, total energy intake, and physical activity; ⁴model 4: adjusted as for model 3 plus glucose, total triglyceride, total cholesterol, and high-density lipoprotein cholesterol; ⁵model 5: adjusted as for model 4 plus body mass index and waist circumference. #: R² change = R²(model (A+1)) − R² (model(A)). hs-CRP: high-sensitivity C-reactive protein; OR: odds ratio; CI: confidence interval.