The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 7

Analyses of covariance comparing DBP values of treated (taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.

Covariate	⁢Regression coefficient for Z (PWH versus NHANES)
		95% CI
Older adults (30–79 years)
No covariates (Cage + Cage^2 + only)	6.40	3.75, 9.05	<0.001	0.165
log BMI	6.13	3.79, 8.47	<0.001	0.175
log (1 + Creatinine)	6.92	4.62, 9.21	<0.001	0.168
eGFR	6.73	4.45, 9.00	<0.001	0.172
log TotalCholesterol	8.53	5.97, 11.10	<0.001	0.224
Diabetes	6.60	4.34, 8.85	<0.001	0.179
Smoking status	6.57	3.95, 9.19	<0.001	0.164
HCV	6.97	3.13, 18.81	<0.001	0.170
Race	6.68	4.42, 8.95	<0.001	0.175
All covariates	6.68	2.26, 11.10	0.003	0.239

indicates the binary variable that distinguishes PWH from NHANES ( for PWH, for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; , regression coefficient for representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; , square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.
Cage, Cage², log BMI, eGFR, log TotalCholesterol, diabetes, smoking status, HCV, and race.