The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 5

Analyses of covariance comparing log SBP values of treated (taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.

Covariate	Regression coefficient for (PWH versus NHANES)
		95% CI
Older adults (30–79 years)
No covariates (age  +   only)	0.047	0.017, 0.078	0.003	0.020
log BMI	0.038	0.011, 0.065	0.006	0.022
log (1 + Creatinine)	0.045	0.019, 0.072	<0.001	0.025
eGFR	0.044	0.018, 0.070	0.001	0.023
log TotalCholesterol	0.064	0.033, 0.095	<0.001	0.050
Diabetes	0.042	0.016, 0.068	0.001	0.024
Smoking status	0.042	0.012, 0.072	0.006	0.027
HCV	0.046	0.002, 0.090	0.039	0.023
Race	0.041	0.015, 0.066	0.002	0.041
All covariates	0.053	0.001, 0.104	0.045	0.087

indicates the binary variable that distinguishes PWH from NHANES ( for PWH, for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; , regression coefficient for representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; , square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.
Age, log BMI, eGFR, log TotalCholesterol, diabetes, smoking status, HCV, and race.