Research Article

Role of Renin-Angiotensin System and Oxidative Stress on Vascular Inflammation in Insulin Resistence Model

Table 3

Cytokine release profiles on different experimental models.

CytokineaRelative levelsbArray locationcFold increase for control group (WKY)d
SHRFFRFFHRFFHR + TFFHR + C

CINC-2HE1-21.181.102.422.07NC
CINC-3HF1-21.341.302.742.00NC
CNTFG1-2
FractalkineH1-2
GM-CSFA4-5
INF- HB3-45.004.505.904.001.50
IL-1 C3-4
IL-1 D3-4
IL-4E3-4
IL-6F3-4
IL-10G3-4
LIXH3-4
LeptinHA5-61.161.332.101.67NC
MCP-1HB5-61.25NC4.002.62NC
MIP-3 HC5-61.161.333.912.501.25
β-NGFHD5-62.402.403.502.93NC
TIMP-1HE5-62.601.522.501.90NC
TNF- HF5-63.191.103.352.801.30
VEGFHG5-62.50NC3.052.60NC

aName of cytokine.
bRelative levels: —: undetectable; H: high; L: low.
cSee Figure 2 for the location of the duplicate spots in the matrix.
dWhen the control “ ” symbol was used to indicate an approximation of zero, the values indicate the fold increase versus Wistar Kyoto (WKY: control group). NC: no change (less than or equal to fold difference from the level in WKY group).