International Journal of Hepatology

Cholangiopathy: Genetics, Mechanism, and Pathology


Publishing date
01 Oct 2011
Status
Published
Submission deadline
01 Apr 2011

1Department of Human Pathology, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan

2Division of Transplantation, Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, US

3Institute of Liver Studies, King's College Hospital, Denmark Hill, London SE5 9RS, UK


Cholangiopathy: Genetics, Mechanism, and Pathology

Description

Cholangiopathy is pathologically and pathogenetically heterogeneous and includes a broad spectrum of clinical manifestations. Recent advances in biology and medicine have introduced new technologies to study the cholangiocyte biologies and physiologies and the genetics, pathogenesis, and pathology of cholangiopathy. Several animal models have been developed for autoimmune and genetic cholangiopathy. Knowledge and understanding of these conditions have led to the development of promising therapies and novel tools to characterize these clinical conditions.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the pathogenesis and pathology of genetic, infectious, immune-mediated, and sclerosing cholangiopathy and the development of strategies to treat these cholangiopathies. We are particularly interested in articles describing the new approaches to the genetic and inflammatory cholangiopathy with respect to animal models and molecular immunologies; new insights into progenitor cells, autophagy, cellular senescence, regeneration, regulatory T cells, and natural killer cells; current concepts in the treatment and diagnosis of cholangiopathy using small molecules, SiRNA, molecular targets, and gene therapy strategies. Potential topics include, but are not limited to:

  • Recent developments in cholangiocyte biologies
  • Advances in molecular and genetic aspects of cholangiopathy
  • Cholangiopathy after liver transplantation: recurrence or rejection
  • Role of chemokines and cytokines in immune-mediated cholangiopathy
  • Innate and acquired immunity to pediatric cholangiopathy and sclerosing cholangitis
  • Cellular senescence and cholangiopathy
  • Animal model of autoimmune cholangiopathy and genetic cholangiopathy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijhep/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 950713
  • - Editorial

Cholangiopathy: Genetics, Mechanism, and Pathology

Yasuni Nakanuma | Anthony J. Demetris | ... | Alberto Quaglia
  • Special Issue
  • - Volume 2012
  • - Article ID 547840
  • - Review Article

Tutorial Review for Understanding of Cholangiopathy

Yasuni Nakanuma
  • Special Issue
  • - Volume 2012
  • - Article ID 793569
  • - Review Article

Cholangiopathy with Respect to Biliary Innate Immunity

Kenichi Harada | Yasuni Nakanuma
  • Special Issue
  • - Volume 2012
  • - Article ID 102839
  • - Research Article

Fractalkine and Other Chemokines in Primary Biliary Cirrhosis

Shinji Shimoda | Carlo Selmi | M. Eric Gershwin
  • Special Issue
  • - Volume 2012
  • - Article ID 649290
  • - Review Article

PBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections

Masashi Ninomiya | Yoshiyuki Ueno | Tooru Shimosegawa
  • Special Issue
  • - Volume 2012
  • - Article ID 472376
  • - Review Article

IgG4 Cholangiopathy

Yoh Zen | Yasuni Nakanuma
  • Special Issue
  • - Volume 2012
  • - Article ID 630543
  • - Review Article

Molecular Pathogenesis of Cholangiocarcinoma

G. Fava | I. Lorenzini
  • Special Issue
  • - Volume 2012
  • - Article ID 452143
  • - Review Article

Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy

Motoko Sasaki | Yasuni Nakanuma
  • Special Issue
  • - Volume 2012
  • - Article ID 107945
  • - Review Article

Caroli's Disease: Current Knowledge of Its Biliary Pathogenesis Obtained from an Orthologous Rat Model

Yasunori Sato | Xiang Shan Ren | Yasuni Nakanuma
  • Special Issue
  • - Volume 2012
  • - Article ID 403954
  • - Review Article

Pathological Features of New Animal Models for Primary Biliary Cirrhosis

Koichi Tsuneyama | Yuki Moritoki | ... | Yasuni Nakanuma
International Journal of Hepatology
 Journal metrics
Acceptance rate-
Submission to final decision70 days
Acceptance to publication22 days
CiteScore2.280
Impact Factor-
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