Liver Injury Patterns and Hepatic Toxicity among People Living with and without HIV and Attending Care in Urban Uganda
Table 2
Baseline social demographic and clinical characteristics of adults with and without HIV and in care at Mulago Hospital Uganda (January 2015-March 2020).
Characteristic
Participants without HIV (%)
Participants with HIV (%)
Overall (%)
value
256 (49.6)
260 (50.4)
516 (100)
Gender
Female
142 (55)
145 (56)
287 (56)
0.945
Male
114 (45)
115 (44)
229 (44)
Mean age (years SD±)
44 (10.2)
44 (10.3)
44 (10.3)
0.577
Mean BMI (years SD±)
27 (10.6)
23 (4.5)
25 (8.2)
<0.001
Ever consumed alcohol
112 (44)
106 (41)
218 (42)
0.493
Ever used tobacco products
44 (17)
40 (15)
84 (16)
0.579
Used herbal medicines in the last 12 months
85 (33)
65 (25)
150 (29)
0.040
HBsAg Positive
7 (3)
36 (14)
43 (8)
<0.001
HCV antibody Positive
8 (3)
7 (3)
15 (3)
0.770
Median ALT (IQR)
17 (13-24)
20 (14-26)
18 (14-26)
<0.001
Median ALP (IQR)
77 (63-99)
90 (66-114)
82 (64-106)
0.004
Median GGT (IQR)
Median TC (IQR)
176 (159-200)
162 (132-190)
173 (147-196)
<0.001
Median LDL-C (IQR)
102 (87-122)
96 (70-112)
98 (77-120)
0.022
Median TG (IQR)
118 (85-164)
119 (83-160)
118 (84-161)
<0.001
Median HDL-C (IQR)
47 (40-56)
40 (31-48)
44 (35-53)
0.010
BMI: body mass index; HBsAg: hepatitis B surface antigen; HCV: hepatitis C; ALT: alanine transferase; ALP: alkaline phosphatase; GGT: gamma glutamyl transferase; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol.
