Inhibition of Gluconeogenesis by Boldine in the Perfused Liver: Therapeutical Implication for Glycemic Control

Figure 6

Concentration dependence of the effects of boldine on alanine gluconeogenesis in the perfused livers from fasted rats. Livers were perfused as described in the Materials and Methods. The metabolic rates were calculated at 36 minutes of perfusion time (control condition, zero boldine concentration; ) and at 5 minutes of perfusion time (). Asterisks () indicate statistically significant differences when compared to the control condition (absence of boldine), as indicated by post hoc testing according to Student-Newman-Keuls ().

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