Research Article

Assessment of Clinical Characteristics and Outcomes of Liver Diseases Unique to Pregnancy at a Tertiary Hospital in Ethiopia: A Retrospective Cohort Study

Table 4

Maternal and neonatal outcomes of liver disease specific to pregnancy.

PE/E with liver dysfunction (%)HELLP syndrome (%)AFLP (%)HG with liver dysfunction (%)Total (%) value (HELLP syndrome+AFLP)

Cesarean section21 (48.8%)16 (45.7%)2 (28.6%)1 (11.1%)40 (42.1%)0.895
AKI on dialysis1 (2.3%)6 (17.1%)2 (28.6%)9 (9.5%)0.009
Abruption of placenta1 (2.3%)7 (20%)2 (28.6%)10 (10.5%)0.004
Liver hematoma or rupture1 (2.9%)1 (1.1%)0.442
ICU admission2 (4.7%)16 (45.7%)5 (71.4%)23 (24.2%)0.001
Maternal death3 (8.6%)1 (14.3%)4 (4.2%)0.035
Miscarriage4 (9.3%)2 (5.7%)6 (6.3%)0.907
Neonatal ICU admission9 (20.9%)5 (14.3%)2 (28.6%)16 (16.8%)0.849
Early neonatal death2 (4.7%)2 (5.7%)4 (4.2%)1.000
Stillbirth5 (11.6%)13 (37.1%)5 (71.4%)23 (24.2%)0.001

PE/E: preeclampsia/eclampsia; HELLP: hemolysis elevated liver enzyme and low platelet; AFLP: acute fatty liver of pregnancy; HG: hyperemesis gravidarum; AKI: acute kidney injury; ICU: intensive critical care unit.