Assessment of Clinical Characteristics and Outcomes of Liver Diseases Unique to Pregnancy at a Tertiary Hospital in Ethiopia: A Retrospective Cohort Study
Table 3
Biochemical characteristics of liver disease specific to pregnancy.
PE/E with liver dysfunction
HELLP syndrome
AFLP
HG with liver dysfunction
value for AFLP and HELLP
Aspartate amino transferase (UI/L)
105.9 (83-180)
276 (120-700)
322 (140-507)
124.5 (96-147.2)
0.921
Alanine aminotransferase (UI/L)
75 (48.8-159.3)
225.8 (115.7-379.6)
87 (43-231)
81.8 (54.6-109.6)
0.076
Total bilirubin (mg/dL)
0.4 (0.2-1.1)
2.9 (1.2-5.5)
13.3 (7.3-16.3)
0.7 (0.5-0.8)
0.005
Direct bilirubin (mg/dL)
0.21 (0.11-0.45)
1.39 (0.56-4.37)
9.73 (6.87-11.9)
0.18 (0.14-0.2)
0.002
Prothrombin time (s)
13 (12-14.6)
13.9 (11.9-20.3)
23 (20.4-25.7)
11.5 (9.7-13)
0.007
International normalization ratio
1.1 (1-1.1)
1.1 (0.9-1.7)
2.2 (1.9-2.4)
0.9 (0.8-1)
0.006
Lactate dehydrogenase
411 (292-516)
1195 (888-2100)
944 (800-1950)
—
0.428
White blood count (cells103/μL)
10.6 (8-12.4)
12.8 (10.6-18.9)
23.8 (17.8-26.6)
8.9 (7.7-9.6)
0.002
Hemoglobin (g/dL)
13.7 (12.7-14.3)
12.2 (9.1-14)
7.9 (6.2-10)
12.1 (12-13.5)
0.026
Platelet (cells103/μL)
175 (157-195)
58 (44-83)
116 (42-183)
235 (207-280)
0.076
Creatinine (mg/dL)
0.7 (0.56-0.88)
1.45 (0.71-3.4)
3.5 (2.44-5.6)
0.67 (0.64-0.87)
0.032
Values are presented as a median and interquartile range. PE/E: preeclampsia/eclampsia; HELLP: hemolysis elevated liver enzyme and low platelet; AFLP: acute fatty liver of pregnancy; HG: hyperemesis gravidarum.
