International Journal of Hepatology / 2022 / Article / Tab 2 / Research Article
Spleen and Liver Stiffness Evaluation by ARFI Imaging: A Reliable Tool for a Short-Term Monitoring of Portal Hypertension? Table 2 HVPG, LSM, and SSM results according to initiated NSBB treatment (NSBB = non-selective beta-blocker; HVPG = hepatic venous pressure gradient; LSM = Liver stiffness measurement; SSM = spleen stiffness measurement). All the values are presented as median values (min–max).
HVPG (mmHg) LSM (m/s) SSM (m/s) upper SSM (m/s) hilar SSM (m/s) bottom SSM (m/s) overall All patients Baseline 18 (10-27) 2.88 (1.31–3.76) 2.55 (0.74–3.39) 2.98 (2.05–4.11) 3.59 (2.8–5.0) 3.00 (2.27–3.59) Follow-up 17 (2–22.0) 2.89 (1.22–3.64) 2.44 (0.84–3.66) 3.21 (2.20–3.95) 3.58 (2.23–3.98) 3.03 (2.33–3.55) Delta (value) -1 0.01 -0.11 0.23 -0.01 0.03 Delta (% baseline) -5.5% 0% -4% 7% 0% 0% Correlation with HVPG results ( - value) Baseline 0.46 ( =0.0089 )0.25 ( =0.17) -0.12 ( =0.51) 0.086 ( =0.64) -0.21 ( =0.239) Follow-up 0.54 ( =0.0016 )0.1 ( =0.59) 0.001 ( =0.97) 0.13 ( =0.47) 0.12 ( =0.49) Delta 0.16 ( =0.381) -0.25 ( =0.17) -0.38 ( =0.03) 0.06 ( =0.77) -0.298 ( =0.114) Responder Baseline 20 (10-27) 2.85 (1.31–3.34) 2.42 (0.74–3.39) 2.54 (2.41–3.42) 3.53 (2.8–4.15) 2.96 (2.27–3.34) Follow-up 15.5 (2–20) 2.83 (1.22–3.28) 2.42 (1.47–3.66) 3.11 (2.26–3.69) 3.44 (2.23–3.98) 3.02 (2.33–3.22) Delta (value) -4.5 -0.02 0 0.57 0.09 +0.06 Delta (% baseline) -29% - 0% 0% 22% -3% + 2% Correlation with HVPG results ( - value) Baseline 0.82 ( = 0.0003 )0.27 ( = 0.33) - 0.17 ( = 0.53) 0.11 ( = 0.69) - 0.33 ( = 0.25) Follow-up 0.73 ( = 0.0026 )0.41 ( = 0.14) 0.09 ( = 0.75) -0.04 ( = 0.88) 0.28 ( = 0.32) Delta 0.40 ( = 0.149) - 0.15 ( = 0.58) - 0.27 ( = 0.34) 0.01 ( =0.94) - 0.27 ( = 0.34) Non-responder Baseline 16 (12-21) 2.88 (2.09–3.76) 2.7 (1.47–3.31) 3.4 (2.05–4.11) 2.7 (1.47–3.32) 3.23 (2.38–3.59) Follow-up 19 (14–22) 3.09 (1.72–3,64) 2.46 (0.84–3.27) 3.24 (2.2–3.95) 2.46 (0.84–3.27) 3.03 (2.41–3.55) Delta (value) 3 0.21 - 0.24 - 0,16 -0,24 - 0.2 Delta (% baseline) 16% 7% - 9% - 5% 9% - 7% Correlation with HVPG results Baseline 0.07 ( = 0.76) - 0,18 ( = 0.48) 0.13 ( =0.59) 0.13 ( = 0.6) 0.06 ( = 0.82) Follow-up -0.01 ( =0.96) - 0.26 ( = 0.31) -0.21 ( = 0.31) 0.25 ( = 0.32) - 0.17 ( = 0.50) Delta - 0.26 ( = 0.31) - 0.49 ( = 0.04) 0.21 ( = 0.4) 0.34 ( =0.17) 0.04 ( = 0.85)