Research Article

Spleen and Liver Stiffness Evaluation by ARFI Imaging: A Reliable Tool for a Short-Term Monitoring of Portal Hypertension?

Table 1

General characteristics of the patients included in the study (BMI = body mass index; MELD = model for end-stage liver disease; ASH = alcoholic steatohepatitis; AICH = autoimmune-cholestatic hepatopathy; NASH = nonalcoholic steatohepatitis; HVPG = hepatic venous pressure gradient; LSM = liver stiffness measurement; SSM = spleen stiffness measurement).

VariableOverall  =31Non-responder  =17Responder  =14-value

Age (years)62 (40-78)62 (43-78)62 (40-71)
Sex
 Female9 (29%)6 (35%)3 (21%)
 Male22 (71%)11 (65%)11 (79%)
BMI (kg/m2)25.2 (16.7–33.4)26.4 (16.7–32.2)24.8 (21.4–33.4)
Obesity
Underweight/normal14 (45%)5 (29%)9 (64%)
Overweight/obesity17 (55%)12 (71%)5 (36%)
Child-Pugh score
 Child A17 (55%)8 (47%)9 (64%)
 Child B14 (45%)9 (53%)5 (36%)
Liver disease etiology
 NASH5 (16%)4 (24%)1 (7.1%)
 ASH14 (45%)7 (41%)7 (50%)
 AICH4 (13%)0 (0%)4 (29%)
 Viral2 (6.5%)2 (12%)0 (0%)
 Other6 (19%)4 (24%)2 (14%)
MELD (pts.)12 (7-19)12 (7-19)10 (7-18)0.3
HVPG baseline (mmHg)18 (10-27)16 (12-21)20.0 (10-27)0.2
LSM baseline (m/s)2.88 (1.31–3.76)2.88 (2.09–3.76)2.84 (1.31–3.34)0.4
SSM overall baseline (m/s)3.0 (2.27–3.59)3.23 (2.38–3.59)2.96 (2.27–3.34)0.04