International Journal of Hepatology

Research Article

Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV Management

Table 7

Analysis of the variation in the levels of GGT, DBIL, and VL with genotype D using multinomial logistic regression analysis.


Variable	Categories	Genotype		COR [95% CI]	AOR [95% CI]	value
Variable	Categories	D, (%)	D/E, (%)			value

GGT (U/L)	Normal	17 (25.4)	26 (38.8)	1	1
GGT (U/L)	Elevated	15 (24.2)	11 (17.7)	2.09 [0.775 to 5.61]	1.82 [0.625 to 5.296]	0.272
DBIL (μmol/L)	Normal	8 (17.0)	10 (21.3)	1	1
DBIL (μmol/L)	Elevated	24 (29.3)	27 (32.9)	1.11 [0.377 to 3.272]	1.26 [0.384 to 4.137]	0.702
VL (IU/mL)	<20,000	23 (50.0)	22 (26.5)	1	1
VL (IU/mL)	≥20,000	9 (10.8)	15 (32.6)	3.748 [1.36 to 10.31]	3.77 [1.32 to 10.756]	0.013

Reference genotype according to the model used for analysis; COR: crude odds ratio; AOR: adjusted odds ratio; GGT: gamma glutamyl transferase; DBIL: direct bilirubin; VL: viral load. significant at 95% confidence interval.