International Journal of Hepatology

Research Article

Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV Management

Table 6

Analysis of the variation in the levels of GGT, DBIL, and VL with genotype A using multinomial logistic regression analysis.


Variable	Categories	Genotype		COR [95% CI]	AOR [95% CI]	value
Variable	Categories	A, (%)	D/E, (%)			value

GGT (U/L)	Normal	24 (35.8)	26 (38.8)	1	1
GGT (U/L)	Elevated	36 (58.1)	11 (17.7)	3.545 [1.48 to 8.496]	6.06 [2.19 to 16.81]	0.001
DBIL (μmol/L)	Normal	29 (61.7)	10 (21.3)	1	1
DBIL (μmol/L)	Elevated	31 (37.8)	27 (32.9)	0.396 [0.163 to 0.959]	0.167 [0.07 to 0.499]	0.001
VL (IU/mL)	<20,000	52 (62.7)	22 (26.5)	1	1
VL (IU/mL)	≥20,000	8 (17.4)	15 (32.6)	0.226 [0.084 to 0.609]	0.146 [0.047 to 0.45]	0.001

Reference genotype according to the model used for analysis; COR: crude odds ratio; AOR: adjusted odds ratio; GGT: gamma glutamyl transferase; DBIL: direct bilirubin; VL: viral load. significant at 95% confidence interval.