Supplementation with Branched-Chain Amino Acids Induces Unexpected Deleterious Effects on Astrocyte Survival and Intracellular Metabolism with or without Hyperammonemia: A Preliminary In Vitro Study

Table 2

Levels of metabolites related to butyric acid metabolism.

Compound name	Comparative analysis
	BCAA vs. control
	Ratio	value
2-Hydroxyglutaric acid	1.0	0.884
3-Hydroxybutyric acid	0.7	0.031
Fumaric acid	0.5	0.008
GABA	0.9	0.158
Glu	1.1	0.298
Malic acid	0.6	0.001
Pyruvic acid	<1	N.A.
Succinic acid	0.4	0.014

Data expressed as the mean value (). and (Welch’s -test).