The Influence of Donor and Recipient Complement C3 Polymorphisms on Liver Transplant Outcome
Table 3
Cox proportional hazards-derived hazard ratios for patient survival, graft survival, and acute rejection in donor/recipient combinations versus the SS/SS reference cohort.
Donor/recipient
Hazard ratio (95% CI)
vs. SS/SS
Patient survival
Graft survival
Acute rejection
FF/FS
0.433 (0.027–6.95)
17.0 (0.943–307)
11.3 (0.401–319)
FF/SS
0.002 (0.001–3.17)
0.002 (0.001–1.459)
0.001 (0.001–89.6)
FS/FF
0.890 (0.004–8.93)
0.003 (0.001–18.7)
0.001 (0.001–94.5)
FS/FS
0.430 (0.092–2.01)
1.413 (0.327–6.11)
2.20 (0.752–6.45)
FS/SS
0.205 (0.047–0.890)
0.919 (0.278–3.04)
1.19 (0.554–2.54)
SS/FF
279 (1.81–43100)
21.9 (1.69–283)
1.54 (0.317–7.48)
SS/FS
0.282 (0.089–0.887)
3.84 (1.32–11.1)
0.327 (0.076–1.41)
Cox regression adjust to donor type, C3 donor, bilirubin day 3, AST day 7, C3 recipient, lactate day 4, C3 recipient, death or alive, lactate day 1, bilirubin day 4, acute rejection, lactate day 3, CIT.
