Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)

Table 2

Factors associated with risk of decompensation on follow-up in patients with cirrhosis of liver.

	Without decompensation events	With decompensation events	value
Mean age (, years)			<0.001
Etiology of CLD ( (%))
Alcohol	31 (42.5)	43 (44.3)
Viral hepatitis	9 (12.3)	2 (2.06)	0.043
Cryptogenic	33 (45.2)	52 (53.6)
Comorbidities ( (%))
Diabetes mellitus	56 (76.7)	54 (55.7)	0.004
Systemic hypertension	26 (35.6)	25 (25.8)	0.166
Coronary artery disease	11 (15.1)	8 (8.2)	0.162
Chronic kidney disease	17 (23.3)	13 (13.4)	0.094
Child status ( (%))
Child A	31 (42.5)	6 (6.2)
Child B	15 (20.5)	17 (17.5)	<0.001
Child C	27 (37)	74 (76.3)
Mean MELD score ()			<0.001
Past history of complications of CLD ( (%))
Varices on endoscopy	57 (78.1)	69 (71.1)	0.306
Ascites	1 (1.4)	66 (68)	<0.001
Hepatic encephalopathy	0 (0)	41 (42.3)	<0.001
Hepatorenal syndrome	0 (0)	45 (46.4)	<0.001
Variceal bleed	23 (31.5)	18 (18.6)	0.006
Laboratory parameters ()
Total cholesterol			0.258
High-density lipoprotein			<0.001
Low-density lipoprotein			0.608
Total leucocyte count			0.048
Platelet count			0.033
Creatinine			0.850
Sodium			0.029
Potassium			0.427
Albumin			<0.001
INR			<0.001
C-reactive protein			0.080
Neutrophil-lymphocyte ratio (NLR)			0.003

Statistically significant (<0.05). Abbreviations: CLD: chronic liver disease; MELD score: model for end-stage liver disease; INR: international normalized ratio.