Research Article

Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)

Table 1

Distribution of variables among patients with decompensation events on follow-up as compared to patients with decompensation.

Baseline characteristics of the populationTotal

Mean age (, years)
Gender distribution ( (%))
Male147 (86.5)
Female23 (13.5)
Median duration of CLD at recruitment (days)1121
Etiology of CLD ( (%))
Alcohol74 (43.5)
Viral hepatitis11 (6.4)
Cryptogenic85 (50)
Comorbidities ( (%))
Diabetes mellitus110 (64.7)
Systemic hypertension51 (30)
Coronary artery disease19 (11.2)
Chronic kidney disease30 (17.6)
Child status ( (%))
Child A37 (21.8)
Child B32 (18.8)
Child C101 (59.4)
Mean MELD score ()
Past history of complications of CLD ( (%))
Varices on endoscopy126 (74.11)
Ascites95 (55.88)
Hepatic encephalopathy44 (25.88)
Variceal bleed41 (24.11)
Laboratory parameters: ()
Total cholesterol
High-density lipoprotein
Low-density lipoprotein
Total leucocyte count
Platelet count
Creatinine
Sodium
Potassium
Albumin
INR
C-reactive protein
Neutrophil-lymphocyte ratio (NLR)
Total decompensation events at follow-up ( (%))97 (57.05)
Ascites67 (69.07)
Hepatic encephalopathy41 (42.26)
Hepatorenal syndrome45 (46.39)
Variceal bleed20 (20.61)
Mortality ( (%))43 (25.3)

Abbreviations: CLD: chronic liver disease; MELD score: model for end-stage liver disease; INR: international normalized ratio.