Research Article
Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)
Table 1
Distribution of variables among patients with decompensation events on follow-up as compared to patients with decompensation.
| Baseline characteristics of the population | Total |
| Mean age (, years) | | Gender distribution ( (%)) | | Male | 147 (86.5) | Female | 23 (13.5) | Median duration of CLD at recruitment (days) | 1121 | Etiology of CLD ( (%)) | | Alcohol | 74 (43.5) | Viral hepatitis | 11 (6.4) | Cryptogenic | 85 (50) | Comorbidities ( (%)) | | Diabetes mellitus | 110 (64.7) | Systemic hypertension | 51 (30) | Coronary artery disease | 19 (11.2) | Chronic kidney disease | 30 (17.6) | Child status ( (%)) | | Child A | 37 (21.8) | Child B | 32 (18.8) | Child C | 101 (59.4) | Mean MELD score () | | Past history of complications of CLD ( (%)) | | Varices on endoscopy | 126 (74.11) | Ascites | 95 (55.88) | Hepatic encephalopathy | 44 (25.88) | Variceal bleed | 41 (24.11) | Laboratory parameters: () | | Total cholesterol | | High-density lipoprotein | | Low-density lipoprotein | | Total leucocyte count | | Platelet count | | Creatinine | | Sodium | | Potassium | | Albumin | | INR | | C-reactive protein | | Neutrophil-lymphocyte ratio (NLR) | | Total decompensation events at follow-up ( (%)) | 97 (57.05) | Ascites | 67 (69.07) | Hepatic encephalopathy | 41 (42.26) | Hepatorenal syndrome | 45 (46.39) | Variceal bleed | 20 (20.61) | Mortality ( (%)) | 43 (25.3) |
|
|
Abbreviations: CLD: chronic liver disease; MELD score: model for end-stage liver disease; INR: international normalized ratio.
|