International Journal of Hepatology / 2019 / Article / Tab 3 / Research Article
Preoperative Neutrophil-to-Lymphocyte Ratio Plus Platelet-to-Lymphocyte Ratio Predicts the Outcomes after Curative Resection for Hepatocellular Carcinoma Table 3 Univariate and multivariate analysis of prognostic factors of recurrence free survival.
Characteristics Univariate Multivariate HR (95% CI) p valueHR (95% CI) p valuePatient factors Age (years) 1.012 0.266 Male sex 1.674 0.174 Hepatitis B 1.072 0.778 Child Pugh B 1.692 0.146 Laboratory data Creatinine 0.998 0.461 ICG>15 1.164 0.677 Surgical factors Major surgery 1.128 0.626 Operation time > 350min 1.474 0.132 EBL>500ml 1.788 0.040 1.781 0.043 Tumor factors AFP >400 1.331 0.388 Size>5cm 1.498 0.100 0.909 0.735 Multiple tumors 1.293 0.374 R1 resection 2.492 0.013 2.340 0.029 Inflammatory indices PLR ≥155 1.717 0.032 NLR ≥ 2.7 1.751 0.032 PLR ≥155 and NLR ≥ 2.7 2.115 0.003 1.917 0.011
HR: hazard ratio, CI: confidence interval, ICG: indocyanine green, EBL: estimated blood loss, AFP: alpha-fetoprotein, NLR: neutrophil-to-lymphocyte ratio, and PLR: platelet-to-lymphocyte ratio.