Betaine Treatment Attenuates Chronic Ethanol-Induced Hepatic Steatosis and Alterations to the Mitochondrial Respiratory Chain Proteome
Figure 5
Betaine has minimal effect on chronic ethanol-dependent increase in CYP2E1 activity and protein. (a) Hepatic CYP2E1 activity was determined as detailed in Section 2. Data represent the mean ± S.E.M. for animal per groups. Values not sharing a common letter are statistically different, . (b) CYP2E1 protein levels were measured by immunoblotting. The bar graph results represent the mean volume integration units (V.I.U) ± S.E.M. for animals per group. Values not sharing a common letter are statistically different, . The top figure shows representative immunoblots of CYP2E1 protein for one pair of untreated and one pair of betaine-treated control and ethanol animals.
