Dose-Dependent Change in Elimination Kinetics of Ethanol due to Shift of Dominant Metabolizing Enzyme from ADH 1 (Class I) to ADH 3 (Class III) in Mouse
Figure 5
Effect of ethanol dose on catalytic efficiency () of liver ADH activity. The apparent and of liver ADH activity were measured using liver extracts from mice 1 h (○) and 4 h (□) after the administration of each dose of ethanol. is expressed per mg of the sum of the ADH 1 and ADH 3 contents. Each plot represents the average value of 3 mice.
