Dose-Dependent Change in Elimination Kinetics of Ethanol due to Shift of Dominant Metabolizing Enzyme from ADH 1 (Class I) to ADH 3 (Class III) in Mouse
Figure 1
Time course of blood ethanol concentration in mice after ethanol administration (i.p.) at various doses. Each plot represents the mean ± SD of 3 mice. ○ 1 g/kg; □ 2 g/kg; ▵ 3 g/kg; ▿ 4.5 g/kg; ⋄ 5 g/kg.