Review Article

A Primer on Detecting Cirrhosis and Caring for These Patients without Causing Harm

Table 1

Clues to the presence of cirrhosis.

Risk factors for liver disease, especially obesity, alcohol use, and high-risk behavior for hepatitis C
Sleep/wake reversal
History of fluid retention, gastrointestinal hemorrhage, or unexplained episodic confusion
Stigmata of cirrhosis, including palmar erythema, vascular spiders, and abdominal wall collaterals
Firm liver and/or enlarged spleen
Jaundice, ascites, or asterixis
Platelet count <160,000 × 10(9)/L
Abnormal liver tests
Prolonged international normalized ratio (INR)
Evidence of cirrhosis and/or portal hypertension on imaging
Unusual sensitivity to coumadin