Gadoxetate Acid-Enhanced MR Imaging for HCC: A Review for Clinicians

Table 1

Major differences between gadoxetate acid and gadobenate dimeglumine.

Properties in comparison	Gadoxetate acid	Gadobenate dimeglumine
% contrast uptake	50%	2–4%
Hepatobiliary phase image acquisition	10–45 minutes postcontrast administration	60–120 min postcontrast administration
Duration of liver enhancement	2 hrs	4 hrs
Clearance	50% biliary excretion, 50% renal excretion	2–4% biliary excretion, 96% renal excretion
Recommended dosage	0.025 mmol/kg, bolus injection at 2 mL/sec	0.1 mmol/kg bodyweight, bolus injection at 2 mL/sec