Research Article

Metabonomic-Transcriptome Integration Analysis on Osteoarthritis and Rheumatoid Arthritis

Table 1

The top 5 differentially expressed gene-metabolite interactions.

MetabolitesDEGsOA_corRA_cordiff.corr

Nacetylaminoacid_29HHAT-0.9520.8331.786
Asparagine_54GYG10.905-0.857-1.762
Unknown_129ULK30.857-0.905-1.762
Malonate_64BCR0.762-0.952-1.714
Glucose_70HHAT-0.9050.8101.714

Notes: DEGs: differentially expressed genes; OA_cor: the correlation between DEGs and metabolites in the osteoarthritis group; RA_cor: the correlation between DEGs and metabolites in rheumatoid arthritis correlation; diff.corr: the DEG-metabolite correlation between the OA group and the RA group; was selected as the cut-off value.