Research Article

A Novel Four-Gene Prognostic Signature as a Risk Biomarker in Cervical Cancer

Figure 2

Screening for DEGs in samples from patients with CC. (a) PCA plot showing significant differential clustering between CC (red spheres) and normal cervical (yellow spheres) tissue samples. (b) Volcano plots depicting changes in mRNA expression between the normal cervical tissue () and CC () groups. There were 106 and 101 mRNAs with that were significantly () upregulated (red) and downregulated (blue) in the CC group compared to the normal cervical tissue group. (c, d) GO and KEGG enrichment analyses of DEGs in CC samples. CC: cervical cancer; DEG: differentially expressed gene; PCA: principal component analysis; FC: fold change; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.
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