Whole-Exome Sequencing Identifies One De Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder

Table 1

Candidate variants from whole-exome sequencing which passed in the validation process. The variants which passed in the segregation process are presented with bold letters.

Position	Gene	Classification	Transcript	HGVS Coding	rsID 138	Family
Chr2: 73675228	ALMS1	Ins	NM_015120	c.1570_1571insCTC	rs34628045	1, 2
Chr2: 88876094	EIF2AK3	Nonsyn SNV	NM_004836	c.2014G>A	rs35226268	2
Chr4: 84240515	HPSE	Nonsyn SNV	NM_001199830	c.481A>C	rs75865093	1
Chr5: 140183237	PCDHA3	Nonsyn SNV	NM_031497	c.2455A>G	rs17844265	2
Chr5: 156721864	CYFIP2	Frameshift Ins	NM_001037333	c.279_280insC	rs5872508	1, 2
Chr6: 132270417	CTGF	Frameshift Del	NM_001901	c.1037delG	rs373467469	2
Chr7: 82581489	PCLO	Ins	NM_033026	c.8780_8781insTGA	rs10630259	1
Chr9: 117853022	TNC	Frameshift Del	NM_002160	c.276delG	rs944510	1
Chr12: 95531341	FGD6	Nonsyn SNV	NM_018351	c.2951G>A		2
Chr14: 21861835	CHD8	Nonsyn SNV	NM_001170629	c.6119A>G	rs148494847	2
Chr17: 26101336	NOS2	Nonsyn SNV	NM_000625	c.1423G>A		2
Chr21: 40883672	SH3BGR	Ins	NM_001001713	c.356_357insAGA	rs3831201	1