MicroRNA in Glioblastoma: An Overview

Table 2

miRNA involved in the regulation of EZH2.

miRNA	Action	Reference
Let-7a	Direct targeting of EZH2 in nasopharyngeal carcinoma, inhibition of glioma growth by targeting K-RAS	[206, 207]
miR-26a	Inhibits growth of nasopharyngeal carcinoma targeting EZH2	[208]
miR-101	miR-101 downregulation in GB results in EZH2-induced proliferation regulating the methylation status of CPBE1	[209, 210]
miR-124	Modulates the proliferation of epatocarcinoma cells by direct targeting of EZH2	[211]
miR-138	Blocks GB tumorigenicity by EZH2-CDK4/6-pRb-E2F1 signaling cascade	[212]
miR-214	Targeting of EZH2 in skeletal muscles	[213]
miR-708	Inhibits GB cell proliferation targeting EZH2, AKT1, MMP2, CCND1, Parp-1, and Bcl-2	[214]