Integrating Biological Covariates into Gene Expression-Based Predictors of Radiation Sensitivity

Figure 2

Biological characteristics differ when considering 35 cell lines versus an expanded set of 48 cell lines. (a) The proportion of RAS wild-type cell lines increased (60% to 69%). (b) The proportion of p53 wild-type cell lines increased (26% to 35%). (c) Tissue of origin of cell lines did not change significantly. (d) Venn diagram showing the lack of concordance in correlation when using a test for correlation () using only RAS mutant or RAS wt cell lines in the 35-cell line set. Only 16 probesets were found correlated in both sets.

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