ATP-Binding Cassette Systems of Brucella

Table 4

ABC system genes absent in at least one species when compared to B. melitensis.

Number	Family	Subfamily	Substrate/ Function	Type	B. melitensis	B. abortus	B. suis	B. ovis	B. canis
				IM	BMEI1851	−	+	+	+
5	CCM		Possibly heme export	IM	BMEI1852	−	+	+	+
				ABC	BMEI1853	−	+	+	+
6	CDI		Involved in cell division	IM	BMEI0073, ftsX	+	+	−	+
				ABC	BMEI0072, ftsE	+	+	−	+
7	CLS		O antigen export system	ABC	BMEI1416, rfbB	−	+	+	+
				IM	BMEI1415, rfbD	−	+	+	+
13	DPL	PRT	Proteases, lipase, S-layer protein export	OMP	BMEI1029	+	−	−	+
14	DPL	CHV	Beta-(1→2) glucan export	IM-ABC	BMEI0984	+	+	−	+
16	DPL	HMT	Involved in mitochondrial export systems	IM-ABC	BMEI1743	−	−	−	−
				IM-ABC	BMEI1742	−	−	+	−
22	FAE		Fatty acid export	IM-ABC	BMEII0976	+	−	+	+
				CYTP	BMEI1040	+	+	−	−
31	ISB (ABCX)		Iron/sulphur centre biogenesis	CYTP	BMEI1042	+	+	−	−
				ABC	BMEI1041	+	+	−	−
				ABC	BMEI0964	+	+	+	−
36	MKL		Involved in toluene tolerance	IM	BMEI0965, ttg2B	+	+	+	−
				SS	BMEI0963, ttg2C	+	+	+	−
				IM	BMEII0087	+	+	+	−
				IM	BMEI0361	−	−	−	−
60	o228		Unknown	MFP	BMEI0359	−	−	−	−
				ABC	BMEI0360	−	−	−	−
				IM	−	BruAb10085	+	+	−
61	o228		Unknown	MFP	−	−	−	−	BCAN_A1712
				ABC	−	BruAb10084	+	+	+
62	o228		Unknown	MFP	−	£	£	BOV_1617	−
				IM-ABC	−	£	£	+	BCAN_A0087

Excludes ABC systems involved in import; −: gene absent in the Brucella species; +: gene present in the Brucella species; £: pseudogene present in the Brucella species; Number: refers to ABC system number in the full inventories/alignments of Brucella ABC systems