Research Article
Relationship between Serum Indoxyl Sulfate and Klotho Protein and Vascular Calcification in Patients with Chronic Kidney Disease Stages 3–5
Table 3
Analysis of clinical indexes in the group with and without abdominal aortic calcification.
| | Group | Nonabdominal aortic calcification (33 cases) | Abdominal aortic calcification (75 cases) | t/x2/z | P value |
| | Age (years) | 44.09 ± 11.65 | 60.71 ± 10.93 | −7.130 | 0.000 | | Male (cases (%)) | 23 (69.70%) | 35 (46.67%) | 4.889 | 0.027 | | BMI (kg/m2) | 25.28 ± 4.23 | 24.46 ± 3.22 | 1.093 | 0.277 | | Hypertension (cases (%)) | 29 (87.88%) | 71 (94.67%) | 1.427 | 0.232 | | Diabetes (cases (%)) | 9 (27.27%) | 44 (58.67%) | 9.038 | 0.003 | | Coronary heart disease (cases (%)) | 6 (18.18%) | 38 (50.67%) | 10.017 | 0.002 | | Ca (mmol/L) | 2.16 (2.04, 2.40) | 1.99 (1.86, 2.05) | −5.872 | 0.000 | | P (mmol/L) | 1.88 ± 0.68 | 2.26 ± 0.66 | −2.748 | 0.007 | | iPTH (pg/mL) | 145.00 (75.86, 431.65) | 484.10 (189.90, 700.10) | −2.801 | 0.005 | | ALB (g/L) | 30.85 ± 4.79 | 31.64 ± 4.36 | −0.842 | 0.402 | | Cr (µmol/L) | 388.0 (207.5, 966.5) | 584.0 (306.0, 758.0) | −0.764 | 0.445 | | CKD stage (cases (%)) | | | 7.069 | 0.008 | | Stages 3-4 | 17 (51.52%) | 19 (25.33%) | | | | Stage 5 | 16 (48.48%) | 56 (74.67%) | | | | IS (pg/mL) | 109.62 (89.98, 196.34) | 438.49 (261.48, 695.30) | −7.190 | 0.000 | | Klotho (ng/mL) | 0.93 (0.85, 1.21) | 0.47 (0.39, 0.58) | −7.558 | 0.000 |
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. BMI, body mass index; iPTH, intact parathyroid hormone; ALB, albumin; Cr, creatinine; CKD, chronic kidney disease; IS, indoxyl sulfate. |
