Research Article
Machine Learning for Predicting Distant Metastasis of Medullary Thyroid Carcinoma Using the SEER Database
Table 1
The detailed demographic information of the patients with MTC.
| | Categories | With DM (n = 138) | Without DM (n = 1911) | value |
| | Age, n (%) | | | <0.001 | | <55 | 47 (34.1%) | 959 (50.2%) | | | ≥55 | 91 (65.9%) | 952 (49.8%) | | | Gender (n%) | | | <0.001 | | Female | 50 (36.2%) | 1149 (60.1%) | | | Male | 88 (63.8%) | 762 (39.9%) | | | Race (n%) | | | 0.891 | | White | 116 (84.1%) | 1619 (84.7%) | | | Black | 14 (10.1%) | 159 (8.3%) | | | Other | 8 (5.8%) | 133 (7.0%) | | | Year of diagnosis | | | 0.367 | | 2004–2009 | 54 (39.1%) | 823 (43.1%) | | | 2010–2015 | 84 (60.9%) | 1088 (56.9%) | | | Spanish-Hispanic-Latino (n%) | | | 0.372 | | Yes | 17 (12.3%) | 289 (15.1%) | | | No | 121 (87.7%) | 1622 (84.9%) | | | MTC subtypes (n%) | | | 0.622 | | MTC with amyloid stroma | 4 (2.9%) | 71 (3.7%) | | | MTC NOSa | 134 (97.1%) | 1840 (93.2%) | | | Laterality (n%) | | | 0.419 | | Unilateral | 138 (100%) | 1902 (99.5%) | | | Bilateral | 0 (0%) | 9 (0.5%) | | | Multifocality (n%) | | | 0.009 | | Solitary tumor | 86 (62.3%) | 1388 (72.6%) | | | Multifocal tumor | 52 (37.7%) | 523 (37.7%) | | | Tumor size (n%) | | | <0.001 | | ≤2 | 27 (19.6%) | 1030 (53.9%) | | | 2–4 | 46 (33.3%) | 594 (31.1%) | | | ≥4 | 65 (47.1%) | 287 (15.0%) | | | Extrathyroidal extension (n%) | | | <0.001 | | Yes | 57 (41.3%) | 309 (16.2%) | | | No | 81 (58.7%) | 1602 (83.8%) | | | Lymph node metastasis (n%) | | | <0.001 | | No | 24 (17.4%) | 1206 (63.1%) | | | Cervical central lymph node | 36 (26.1%) | 288 (15.1%) | | | Cervical lateral lymph node | 70 (50.7%) | 359 (18.8%) | | | Yes NOS | 8 (5.8%) | 58 (3.0%) | |
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MTC, medullary thyroid carcinoma; DM, distant metastasis; NOS, not otherwise specified.
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