GLP1R rs3765467 Polymorphism Is Associated with the Risk of Early Onset Type 2 Diabetes

Table 2

Allele frequency of GLP1R SNPs.

SNP ID	REF	ALT	Control (R/A)	EOD (onset age ≤45 yr) (R/A)	LOD (onset age> 45 yr) (R/A)	value
rs3765468	G	A	245/45^a	218/56^a	304/54^a	0.158
rs3765467	G	A	201/89^a	226/48^b	268/90^a,b	<0.001
rs2235868	A	C	156/134^a	168/101^a	202/152^a	0.192
rs1042044	A	C	134/156^a	142/132^a	176/182^a	0.409
rs761387	A	G	239/41^a	193/47^a	260/44^a	0.206
rs761386	C	T	244/42^a	221/51^a	305/51^a	0.269
rs5875654	CAG	C	245/43^a	218/54^a	305/51^a	0.141
rs1126476	A	C	152/138^a	166/108^a	200/158^a	0.145
rs1820	T	A	267/23^a	251/23^a	335/23^a	0.611
rs4714210	A	G	207/81^a	194/78^a	253/103^a	0.978
rs4714211	A	G	178/110^a	164/110^a	221/137^a	0.872
rs10305525	C	A	190/96^a	179/93^a	237/119^a	0.984
rs9296291	T	C	216/70^a	206/64^a	278/74^a	0.547
rs117424338	C	T	268/22^a	254/20^a	335/23^a	0.832
rs9918349	G	A	248/42^a	238/36^a	314/44^a	0.708

REF: the base of the reference genome; ALT: the bases of a mutant genome; R/A: the ratio of the number of REF to that of ALT. -value for comparison of the EOD and control groups. ^aNo significant difference between the EOD group and control group and between the LOD group and control group. ^bSignificant difference between the EOD group and control group. ^a,bSignificant difference between the LOD group and control group.