Research Article

Identification of Risk Factors and Development of a Predictive Model for Postoperative Hypoglycemia among Diabetic Patients during the Perioperative Period

Table 1

Comparisons of demographics and clinical indicators.

CharacteristicHypoglycemia group (n = 109)Nonhypoglycemia group (n = 331) value

Sex (male/female) n (%)68 (62.39)/41 (37.61)204 (61.6)/127 (38.4)0.888
Age (years)63.84 ± 10.362.26 ± 10.810.180
Smoking history (yes)24 (22.02)55 (16.6)0.202
Drinking history (yes)13 (11.93)30 (9.1)0.584
Family history (yes)50 (45.87)141 (42.60)0.550
History of hypertension (yes)60 (55.05)186 (56.20)0.908
BMI (kg/m2)24.00 (21.45, 26.74)24.68 (22.86, 27.3)0.007
Duration of diabetes (years)10 (5, 12.5)6 (2, 10)0.002
Preoperative C-peptide (pmol/L)524.6 (332.1, 858.7)685.95 (492.98, 937.55)0.004
Postprandial C-peptide (pmol/L)1222.5 (685, 2246.75)1561 (1060, 2483)0.102
HbA1c (%)7.8 (6.8, 9.225)8.4 (7.3, 9.7)0.043
Preoperative fasting blood glucose (mmol/L)6.51 (5.10, 9.23)7.99 (6.66, 10.65)<0.001
AST (U/L)17.2 (11.8, 28.2)20.2 (13.3, 32.8)0.107
ALT (U/L)17.3 (14.1, 23.4)18.6 (14.33, 24.98)0.673
UA (mmol/L)312 (246, 393)326 (254, 399)0.189
eGFR (ml·min−1·(1.73 m2)−1)113 (88.8, 135.5)116.2 (94.225, 137.9)0.395
TG (mmol/L)1.19 (0.8, 1.68)1.37 (0.98, 2.0775)0.003
TC (mmol/L)4.13 (3.25, 4.75)4.23 (3.415, 5.0575)0.112
HDL-C (mmol/L)1.07 (0.86, 1.43)1.02 (0.83, 1.2375)0.031
LDL-C (mmol/L)2.27 ± 0.862.44 ± 0.90.102
In-hospital blood glucose management0.017
 Department self-management50 (45.9)115 (34.7)
 Endocrinology consultation management36 (33)99 (29.9)
 Hospital blood glucose management23 (21.1)117 (35.3)
Level of surgery0.120
 I1 (0.90)0 (0.00)
 II3 (2.80)10 (3.00)
 III14 (12.80)66 (20.10)
 IV91 (83.50)253 (76.90)
Incision type0.172
 I10 (9.30)37 (11.30)
 II51 (47.20)181 (55.20)
 III47 (43.50)107 (32.60)
 IV0 (0.00)3 (0.90)
Operation duration (h)3.58 ± 1.943.02 ± 1.790.006
Intraoperative blood loss (ml)0.215
 ≤20053 (52.50)185 (59.50)
 >20048 (47.50)126 (40.50)
Hospital stays (days)18 (13.5, 23)16(11, 22)0.038
Wound healing time (days)9 (6, 11)7 (5, 10)0.002