Association between the Triglyceride Glucose Index and Hyperuricemia in Patients with Primary Hypertension: A Cross-Sectional Study

Table 1

Baseline characteristics of the study participants with different grades of hypertension.

	Total (n = 1707)	Grades 1-2 hypertension (n = 899)	Grade 3 hypertension (n = 808)	value
TyG	8.71 ± 0.58	8.67 ± 0.56	8.74 ± 0.60	0.02
Sex, n (%)				0.25
Male	786 (46.0)	402 (44.7)	384 (47.5)
Female	921 (54.0)	497 (55.3)	424 (52.5)	0.25
Age, years	62.97 ± 12.87	62.78 ± 12.50	63.17 ± 13.28	0.53
Age groups, n (%)				0.21
<65 years	906 (53.1)	490 (54.5)	416 (51.5)
≥65 years	801 (46.9)	409 (45.5)	392 (48.5)
ALB, g/L	43.76 ± 3.92	43.87 ± 3.78	43.62 ± 4.07	0.19
LDL-C, mmol/L	2.58 ± 0.88	2.56 ± 0.87	2.59 ± 0.89	0.51
HDL-C, mmol/L	1.48 ± 0.40	1.50 ± 0.40	1.46 ± 0.41	0.06
AST, U/L	22.56 ± 10.84	22.34 ± 9.72	22.81 ± 11.97	0.38
Scr, μmol/L	79.63 ± 18.16	79.38 ± 17.97	79.90 ± 18.39	0.56
BNU, mmol/L	5.22 ± 1.42	5.17 ± 1.33	5.27 ± 1.50	0.17
UA, μmol/L	343.43 ± 83.93	335.95 ± 84.07	351.76 ± 83.03	<0.001
Glucose, mmol/L	5.31 ± 0.96	5.25 ± 0.72	5.38 ± 1.17	0.004
TC, mmol/L	4.83 ± 1.06	4.80 ± 1.05	4.85 ± 1.07	0.37
INR	1.00 ± 0.11	1.00 ± 0.10	1.01 ± 0.12	0.42
eGFR, mL/min per 1.73 m^2	90.17 ± 31.15	89.88 ± 24.96	90.49 ± 36.84	0.68
HUA, n (%)	313 (18.3)	151 (16.8)	162 (20)	0.08
hs-CRP, mg/L	2.1 (1.7, 3.1)	2.1 (1.7, 2.9)	2.2 (1.8, 3.3)	0.01
ALT, U/L	16.3 (11.9, 24.1)	16.2 (11.9, 24.1)	16.5 (11.8, 24.1)	0.48
HCY, μmol/L	9.1 (6.0, 12.3)	9.0 (6.0, 12.2)	9.4 (6.0, 13.0)	0.14
LPa, mg/dL	76.8 (37.2, 172.9)	79.9 (38.0, 175.3)	72.8 (36.0, 171.5)	0.28
D-dimer, mg/L	0.3 (0.2, 0.5)	0.3 (0.2, 0.5)	0.3 (0.2, 0.5)	0.51
TG, mmol/L	1.4 (1.0, 2.0)	1.4 (1.0, 1.9)	1.4 (1.0, 2.0)	0.07

Data are presented as the mean ± SD or median (interquartile range) for skewed variables or as numbers (%) for categorical variables. TyG: triglyceride-glucose index; ALB: serum albumin; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; AST: aspartate aminotransferase; Scr: blood creatinine; BUN: blood urea nitrogen; UA: uric acid; TC: total cholesterol; INR: international normalized ratio; eGFR: estimated glomerular filtration rate; HUA: hyperuricemia; hs-CRP: high-sensitivity C-reactive protein; ALT: alanine aminotransferase; HCY: homocysteine; LPa: lipoprotein a; and TG: triglyceride. Statistically significant P-values in bold for a better follow-up of the results. The bold values mean that the difference between the two groups is significant.