Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients

Figure 2

Heatmaps of the top 30 differential metabolites in the COM and MF groups before and after treatment. Heatmap: the color indicates the relative expression level of the metabolite in this group of samples. The corresponding relationship between the color gradient and the numerical value is shown in the gradient color block. The right side is the metabolite VIP bar chart. The length of the bar represents the contribution value of the metabolite to the difference between the two groups (VIP > 1), the larger the value, the greater the difference between the two groups. The color of the bar indicates the significance of the difference between the two groups of metabolites, namely, the value. The smaller the value is, the darker the color is. , , . (a) Heatmap of the top 30 VIP metabolites that were differentially expressed in the COM group. (b) Heatmap of the top 30 VIP metabolites that were differentially expressed in the MF group.

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(b)