Risk Factor Analysis and Prediction of Severe Hypocalcemia after Total Parathyroidectomy without Auto-Transplantation in Patients with Secondary Hyperparathyroidism
Table 2
Univariate logistic regression analysis of SH presence based on preoperative data in the training cohort.
Variable
OR (95%CI)
P value
Gender, male vs female
1.461 (0.795–2.685)
0.222
Age (y)
0.929 (0.903–0.957)
<0.001
BMI, >25 vs ≤25 (kg/m2)
1.328 (0.629–2.742)
0.444
Underlying diseases
Diabetic nephropathy vs glomerulonephritis
0.418 (0.021–2.676)
0.434
Hypertensive nephropathy vs glomerulonephritis
2.436 (0.612–9.477)
0.194
Polycystic kidney vs glomerulonephritis
0.731 (0.102–3.397)
0.713
Others vs glomerulonephritis
1.462 (0.468–4.371)
0.501
Unknown vs glomerulonephritis
1.139 (0.541–2.488)
0.737
Duration of dialysis (y)
0.935 (0.858–1.021)
0.133
Dialysis modality, peritoneal dialysis vs hemodialysis
3.443 (0.880–14.369)
0.073
iPTH, >1000 vs ≤1000 (pg/mL)
2.250 (1.789–15.403)
0.003
Alkaline phosphatase, >420 vs ≤420 (U/L)
7.893 (3.709–16.797)
<0.001
Serum calcium (mmol/L)
0.025 (0.005–0.118)
<0.001
Serum phosphate (mmol/L)
1.389 (0.800–2.411)
0.243
Serum kalium (mmol/L)
0.765 (0.491–1.191)
0.236
Hemoglobin (g/L)
0.976 (0.959–0.993)
0.006
Albumin (g/L)
0.902 (0.834–0.975)
0.009
Serum creatinine (μmol/L)
1.000 (0.999–1.002)
1.000
Blood urea nitrogen (mmol/L)
1.018 (0.972–1.066)
0.449
Prothrombin time (s)
1.629 (1.098–2.417)
0.015
Fibrinogen (g/L)
1.023 (0.923–1.134)
0.666
BMI: body mass index; iPTH: intact parathyroid hormone; OR: odds ratio; CI: confidence interval.
