Elevated Thyroglobulin Antibody Level is Associated with Decreased Anti-Müllerian Hormone in Women of Reproductive Age

Table 1

Baseline characteristics of study subjects.

	Total (n = 483)	Low AMH group (n = 48)	Normal AMH group (n = 388)	High AMH group (n = 47)	values
Age (years)	33.77 ± 7.47	34.88 ± 5.92	33.61 ± 7.32	32.14 ± 4.89	0.819
TSH (μIU/mL)	2.68 (1.78–4.24)	3.02 (1.46–4.32)	2.69 (1.81–4.21)	2.31 (1.70–4.18)	0.619
FT4 (ng/dl)	1.26 ± 0.45	1.22 ± 0.29	1.25 ± 0.44	1.33 ± 0.63	0.482
FT3 (pg/ml)	3.15 ± 1.56	3.11 ± 0.56	3.12 ± 1.59	3.38 ± 1.99	0.568
TPOAb (IU/mL)	13.48 (9.02–26.38)	14.96 (8.66–119.93)	13.33 (8.87–24.93)	15.06 (10.24–25.72)	0.394
TgAb (IU/mL)	13.56 (10.0–82.06)	37.62 (13.10–232.68)^#	12.46 (10.0–67.04)	13.61 (10.0–95.74)	≤0.01
AMH (ng/mL)	1.72 (0.33–4.27)	0.01 (0.01–0.024)	1.73 (0.53–3.83)	9.08 (7.91–11.71)	≤0.01

TSH, thyroid-stimulating hormone; FT4, free thyroxine; FT3, free triiodothyronine; TPOAb, thyroid peroxidase antibody; TgAb, thyroglobulin antibody; AMH, anti-Müllerian hormone. Note. Rank the TgAb data and use the rank order as the measurement variable for ANOVA analysis, there is a statistical difference, and value is 0.001. Furthermore, pairwise comparison results show that a statistical difference between low and normal ovarian reserve (); ^#a statistical difference between low and high ovarian reserve ().