Glucose Metabolism Indices and the Development of Chronic Kidney Disease: A Cohort Study of Middle-Aged and Elderly Chinese Persons

Table 2

Pearson’s correlation and multiple regression analyses of baseline glucose indexes associated with UACR and eGFR at follow-up.

	UACR (mg/g)				eGFR
	r		St. β		r		St. β
FPG	0.12	<0.0001	0.12	<0.0001	−0.09	<0.0001	−0.05	<0.0001
OGTT 2 h glucose	0.12	<0.0001	0.11	<0.0001	−0.07	<0.0001	−0.02	0.0874
HbA1c	0.12	<0.0001	0.11	<0.0001	−0.11	<0.0001	−0.06	<0.0001
Fasting insulin	0.11	<0.0001	0.10	<0.0001	−0.03	0.0218	−0.04	0.0028
HOMA-IR	0.14	<0.0001	0.13	<0.0001	−0.06	<0.0001	−0.05	0.0001
HOMA-β	0.02	0.2071	0.01	0.3651	0.05	0.0003	0.01	0.6249

FPG: fasting plasma glucose; OGTT: oral glucose tolerance test; HOMA-IR: homeostasis model assessment of insulin resistance; HOMA-β: homeostasis model assessment-β; UACR: urinary albumin-to-creatinine ratio; eGFR: estimated glomerular filtration rate. All parameters were logarithmically transformed prior to analysis due to non-normal distributions. r: correlation coefficient; St. β: standardized regression coefficient; multiple regression analysis is adjusted for age and sex.