Establishment and Validation of a New Predictive Model for Insulin Resistance based on 2 Chinese Cohorts: A Cross-Sectional Study

Table 4

The AUC, sensitivity, specificity, and cut-off points for each index for predicting IR.

Indexes	AUC		Sensitivity		Specificity		Cut-off values
	Derivation cohort	Validation cohort	Derivation cohort	Validation cohort	Derivation cohort	Validation cohort	Derivation cohort	Validation cohort
Predictive model	0.77	0.91	0.62	0.82	0.81	0.89	8.18	7.46
TyG index	0.69	0.84	0.81	0.86	0.48	0.77	1.60	0.81
LAP	0.66	0.89	0.81	0.86	0.46	0.82	33.54	42.48
VAI	0.63	0.85	0.86	0.86	0.40	0.72	1.44	1.20
THR	0.53	0.83	0.70	0.84	0.41	0.75	1.14	0.73

IR: insulin resistance, AUC: area under the curve, TyG: triglyceride and glucose, LAP: lipid accumulation product, VAI: visceral adiposity index, and THR: triglyceride to high-density lipoprotein cholesterol ratio.