Establishment and Validation of a New Predictive Model for Insulin Resistance based on 2 Chinese Cohorts: A Cross-Sectional Study

Table 2

Univariate logistic regression analysis of factors affecting IR.

Characteristics	OR	95% CI	Wald χ^2
Female	1
Male	0.899	0.628–1.259	0.439	0.507
Age (y)	0.998	0.982–1.014	0.076	0.782
Smoking, n (%)	0.768	0.554–1.084	2.259	0.133
Drinking, n (%)	0.860	0.597–1.240	0.650	0.420
Hyperuricemia, n (%)	1.639	0.831–3.232	2.033	0.154
Dyslipidemia, n (%)	1.386	0.982–1.957	3.441	0.064
NAFLD, n (%)	1.964	1.379–2.796	14.011	<0.001
Hypertension, n (%)	0.916	0.587–1.429	0.150	0.698
BMI (kg/m^2)	1.177	1.116–1.241	36.311	<0.001
VFA (cm^2)	1.018	1.012–1.025	31.913	<0.001
WC (cm)	1.052	1.034–1.070	32.910	<0.001
FPG (mmol/L)	1.312	1.210–1.422	43.424	<0.001
FINS (μU/mL)	1.907	1.701–2.138	122.162	<0.001
TG (mmol/L)	1.365	1.156–1.613	13.456	<0.001
HDL-C (mmol/L)	1.166	0.686–1.981	0.322	0.570
LDL-C (mmol/L)	1.177	0.951–1.456	2.249	0.134
ALT (IU/L)	1.019	1.009–1.030	12.751	<0.001
AST (IU/L)	1.026	1.007–1.046	7.438	0.006
UA (μmol/L)	1.003	1.000–1.005	5.447	0.020

IR: insulin resistance; OR, odds ratio, CI: confidence interval, NAFLD: nonalcoholic fatty liver disease, BMI: body mass index, VFA: visceral fat area, WC: waist circumference, FPG: fasting plasma glucose, FINS: fasting insulin, TG: triglyceride, HDL-C: high-density lipoprotein cholesterol, LDL-C: low density lipoprotein cholesterol, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and UA: uric acid.