Changes in Cross-Sectional Area of the Median Nerve and Body Composition Parameters after Treatment of Acromegaly: 1 year Follow-Up
Table 1
Baseline characteristics of subjects.
Characteristics
Acromegalic patients (n = 30)
Control group (n = 30)
value
Sex (M/F)
12/18
12/18
Age (year)
52 [43–59]
53 [42–61]
ns
GH (ng/ml)
6.50 [3.03–10.79]
0.19 [0.13–0.25]
<0.001
IGF-1 (ng/ml)
526 [372–686]
139 [113–162]
<0.001
Anthropometric measurements
Height (cm)
171 [166–180]
168 [164–175]
Ns
Weight (kg)
89 [74–108]
89 [70–102]
Ns
BMI (kg/m2)
30.8 [25.0–34.1]
31.3 [25.3–34.8]
Ns
Ultrasonography
CSA of the median nerve (mm2)
13.1 [12.2–14.9]
7.5 [6.4–8.4]
<0.001
DXA measurements
Fat mass (kg)
30.1 [23.1–36.9]
31.3 [26.3–37.1]
Ns
Lean mass (kg)
60.4 [47.1–74.9]
49.1 [42.8–66.1]
0.033
Data are presented as median (standard interquartile range). The level of significance was set at . GH: growth hormone, IGF-1: insulin-like-growth factor 1, BMI: body mass index, CSA: cross-sectional area, and DXA: dual-energy X-ray absorptiometry.
