Distinct Gut Microbiota Structure and Function of Children with Idiopathic Central and Peripheral Precocious Puberty

Figure 4

The distribution of the predicted GM function in the PPP and healthy groups. In the heatmap, the contributions of the top 10 genera on 38 KEGG functional categories were detected in the PPP and HC groups (a), and ICPP and HC groups (c), respectively. The deeper red square means the genera contribute to the functional category importantly, while the deeper green square means the functional category obtained less contribution from the genera. The enriched pathways were compared between the PPP and HC groups (b), and the ICPP and HC groups (d) and shown in the box plot. The asterisks indicated their -values. , , , and stand for the -value smaller than 0.05, 0.01, 0.001, and 0.0001, respectively.

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