Research Article

Influence of Obesity Parameters on Different Regional Patterns of Lymph Node Metastasis in Papillary Thyroid Cancer

Table 5

Relationship between BSA and different regional lymph node involvement in men.

Univariate analysis
Nonobesity (BSA)Obesity (BSA) value

Rate of LNM
 Rate of total LNM44 (71.0%)143 (68.1%)0.668
 Rate of CLNM43 (69.4%)137 (65.2%)0.547
 Rate of total LLNM16 (25.8%)61 (29.0%)0.619
 Rate of level II metastasis4 (6.5%)29 (13.8%)0.119
 Rate of level III metastasis11 (17.7%)47 (22.4%)0.433
 Rate of level IV metastasis12 (19.4%)52 (24.8%)0.378
 Rate of level V metastasis2 (3.2%)19 (9.0%)0.131

Number of LNM
 Number of CLNM2.3 (2.4)2.7 (3.3)0.468
 Number of LLNM5.2 (4.0)5.5 (4.1)0.759

LNR
 Central LNR0.34 (0.31)0.36 (0.37)0.684
 Lateral LNR0.04 (0.09)0.08 (0.28)0.316

Pattern of LNM
 Skip metastasis1 (1.6%)6 (2.9%)0.930
 MLLNM14 (22.6%)54 (25.7%)0.617
 Simultaneous metastasis in LC9 (14.5%)49 (23.3%)0.136

The categorical variables were expressed as n (%). The continuous variables were expressed as the mean (standard deviations). Multivariate analysis was expressed as adjusted odds ratio (95% CI). BSA, body surface area; LNM, lymph node metastasis; LLNM, lateral lymph node metastasis; CLNM, central lymph node metastasis; MLLNM, multiple lateral lymph node metastasis; LNR, lymph node ratio; and LC, lateral compartment. Age (per 10 years), glucose, thyroid stimulating hormone, cholesterol, triglyceride, tumor size, multifocality, extrathyroidal extension, and chronic lymphocytic thyroiditis as covariates to adjust OR value.