Research Article
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells
Figure 3
Sestrin2 overexpression ameliorates TM-induced HepG2 cells apoptosis. (a) Representative western-blot results of proteins involved with cell apoptosis (b) Quantitative analysis of proteins involved with cell apoptosis (unpaired two-tailedt-test; for Bax/Bcl2: t(4) = 3.03, ; for C-caspase3/caspase3: t(4) = 3.33, ; for CytoC: t(4) = 3.19, ). (c) Representative images of TUNEL positive HepG2 cells in indicated groups. Scale bar, 50 μm. .
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