Heterogeneity of IGF-1 Levels in Children with hCG-Induced Precocious Puberty

Figure 1

Serum IGF1 SDs/IGFBP-3 SDs in 30 boys with hCG-induced precocious puberty at diagnosis (pre), at the time when hCG level normalized (mid), at the end of multidisciplinary therapy to hCG-secreting tumors (post), and at the final follow-up visit (final). (a) IGF-1 SDs in different therapeutic phases. (b) IGFBP-3 SDs in different therapeutic phases. A total of 11 boys received IGF1 assessment and 4 boys received IGFBP-3 SD assessment (corresponding with Table 1) in the whole therapeutic process and they were marked with blue lines.

(a)

(b)