The Association of Autoimmune Diseases with Type 1 Diabetes Mellitus in Children Depends Also by the Length of Partial Clinical Remission Phase (Honeymoon)

Table 5

Occurrence times for other autoimmune diseases related to the onset of diabetes mellitus.

	Minimum	Maximum	Mean
Diabetes mellitus + celiac disease (26 patients)	64	2768	800
Diabetes mellitus + hashimoto thyroiditis (29 patients)	27	3072	1382
Diabetes mellitus + granuloma annulare (1 patient)	498	498	498
Diabetes mellitus + rheumatoid arthritis (1 patient)	−1297	−1297	−1297
Diabetes mellitus + hereditary progressive spastic paraparesis (1 patient)	1020	1020	1020
Diabetes mellitus + graves’ disease (1 patient)	−408	−408	−408
Diabetes mellitus + vitiligo (1 patient)	2032	2032	2032

26 patients were followed-up with celiac diseases. Occurrence time after DM diagnosis for celiac disease is minimum 64 days and maximum 2768 days. Mean occurrence time for these 26 patients is 800 days. 29 patients were followed-up with Hashimoto thyroiditis. Occurrence time after DM diagnosis for Hashimoto thyroiditis is minimum 27 days and maximum 3072 days. Mean occurrence time for these 29 patients is 1382 days. 1 Rheumatoid arthritis and 1 Graves’ disease were diagnosed before DM diagnosis. Celiac disease comes up about 2 years after the onset of DM and Hashimoto thyroiditis comes up about 4 years after the onset of DM.