Research Article

The Association of Autoimmune Diseases with Type 1 Diabetes Mellitus in Children Depends Also by the Length of Partial Clinical Remission Phase (Honeymoon)

Table 3

Prevalence of other autoimmune diseases associated with diabetes mellitus in patients without, with less and more than 297 days partial clinical remission.

Without partial clinical remissionPartial clinical Remission <297 daysPartial clinical Remission ≥ 297 days

Diabetes mellitus26 (74%)11 (61%)68 (64%)
Diabetes mellitus + 1 other autoimmune disease8 (23%)5 (28%)35 (33%)
Diabetes mellitus + 2 other autoimmune diseases1 (3%)2 (11%)3 (3%)

Eight (23%) of the patients who did not experience a phase of Partial Clinical Remission had been followed-up with DM and 1 other autoimmune disease. Five (28%) of the patients who experienced less than 297 days, a phase of Partial Clinical Remission had been followed-up with DM and 1 other autoimmune disease. Thirty-five (33%) of the patients who experienced more than 297 days a phase of Partial Clinical Remission had been followed-up with DM and 1 other autoimmune disease. This results show that clinicians should be more careful for the other autoimmune diseases, with the patients who experience longer Partial Clinical Remission.