The Impact of Preconceptional Serum TSH Levels between 2.5 and 4.0 mIU/L on Infertile Women Going through Their First IUI Treatment Cycle
Table 1
The characteristics of the included infertile couples.
TSH [0.4–2.5)c (n = 850)
TSH [2.5–4.0)c (n = 635)
AIH
AID
TSH [0.4–2.5)c (n = 552)
TSH [2.5–4.0)c (n = 409)
TSH [0.4–2.5)c (n = 298)
TSH [2.5–4.0)c (n = 226)
Female age (years)a
30.39 (4.58)
30.13 (4.44)
0.262
31.01 (4.56)
30.82 (4.36)
0.529
29.26 (4.4)
28.87 (4.31)
0.314
Partner age (years)a
30.58 (4.89)
30.32 (4.9)
0.309
31.22 (5.12)
31.12 (4.91)
0.748
29.38 (4.19)
28.87 (4.54)
0.179
BMI (kg/m2)a
23.12 (3.15)
23.59 (3.59)
0.030
23.12 (3.1)
23.63 (3.44)
0.016
23.12 (3.26)
23.53 (3.86)
0.187
AMH (ng/ml)a
5.24 (3.92)
5.03 (3.78)
0.306
5.45 (4.17)
5.3 (4.02)
0.593
3.84 (3.36)
4.53 (3.28)
0.295
VD-total (nmol/L)
32.32 (14.21)
32.52 (14.3)
0.791
31.83 (14.16)
30.82 (12.97)
0.258
33.22 (14.26)
35.67 (16.3)
0.070
Endometrial thickness (mm)a
5.99 (2.36)
6.02 (2.07)
0.803
5.94 (3.49)
5.84 (1.91)
0.477
6.07 (2.1)
6.34 (2.3)
0.163
Infertility duration (years)a
3.29 (2.32)
3.58 (2.65)
0.032
3.32 (2.11)
3.46 (2.09)
0.761
3.23 (2.68)
3.99 (3.41)
0.005
FT4 (pmol/L)a
15.47 (2.16)
15.47 (2.05)
0.806
15.5 (2.18)
15.55 (2.04)
0.738
15.41 (2.12)
15.27 (2.06)
0.453
FT3 (pmol/L)a
5.26 (0.69)
5.29 (0.71)
0.421
5.2 (0.7)
5.27 (0.76)
0.171
5.36 (0.65)
5.33 (0.6)
0.504
Infertility type (n)b
Primary infertility
551 (64.82%)
424 (66.77%)
0.434
323 (58.51%)
239 (58.44%)
0.98
228 (76.51%)
185 (81.86%)
0.138
Secondary infertility
299 (35.18%)
211 (33.23%)
229 (41.49%)
170 (41.56%)
70 (23.49%)
41 (18.14%)
Ovulation type (n)b
Nature cycle
495 (58.24%)
363 (57.17&)
0.68
295 (53.44%)
214 (52.32%)
0.731
200 (67.11%)
149 (65.93%)
0.776
Stimulated cycle
355 (41.76%)
272 (42.83)
257 (46.56%)
195 (47.68%)
98 (32.89%)
77 (34.07)
Times of insemination
Single insemination
20 (2.35%)
7 (1.10%)
0.074
9 (1.63%)
4 (0.98%)
0.574
11 (3.69%)
3 (1.33%)
0.109
Double insemination
830 (97.65%)
628 (98.90%)
543 (98.37%)
405 (99.02%)
287 (96.31%)
223 (98.67%)
Causes of infertility (n)b
Female factors
221 (26.00%)
174 (27.40%)
0.716
217 (39.31%)
173 (42.30%)
0.12
4 (1.34%)
1 (0.44%)
0.406
Male factors
317 (37.29%)
230 (36.22%)
91 (16.49%)
52 (12.71%)
226 (75.84%)
178 (78.76%)
Unexplained factors
194 (22.82%)
134 (21.10%)
194 (35.14%)
133 (32.52%)
0 (0)
1 (0.44%)
Others
118 (13.88%)
97 (15.28)
50 (9.06%)
51 (12.47%)
68 (22.82)
46 (20.35%)
aData are expressed as the mean (±SD); bdata are expressed as n (%); c: mIU/L. AIH : artificial insemination by husband; AID : artificial insemination by donor.
